His self-titled label produced eveningwear and daytime styles for the wholesale, ready-to-wear market, from 1961 to 1991. While he was known for his use of chiffon, Stavropoulos also created notable designs in lace, lamé, suede, and taffeta. Stavropoulos, born in Greece, believed in classic design and found inspiration in the simplicity of ancient Greek sculpture. Renowned for his innovative draping techniques, Stavropoulos created every piece in his collection and produced the entire line in his 57th Street atelier. For each spring and fall runway presentation, Stavropoulos created about one hundred designs and held his shows at the luxurious Regency Hotel, in Manhattan. Buyers from the most important stores in New York attended each show, as well as socialites and celebrities. Stavropoulos initially became known for dressing Lady Bird Johnson during her White House years and created looks for other popular figures throughout his career.
Fiercely independent, Stavropoulos did not participate in the licensing agreements popular with other designers of his time or join the Council of Fashion Designers of America (CFDA). Stavropoulos believed in his own fashion philosophy and refused to adhere to the ephemeral nature of fashion, creating sophisticated styles that incorporated classic design and subtle innovation.